In the 1970s and 1980s, Dr. Levey was a basic research pioneer innovator in the fields of immunology and surgical transplantation.  His major discoveries and surgical accomplishments include:
 
    • The first demonstration that the thymus gland secretes an immunologically active hormone
    • The  first, most important series of renal transplants in the very young, which demonstrated the feasibility of successfully using adult kidneys in babies
    • The description of an immunosuppressive regimen that allowed children to grow
    • An important contribution to the treatment of a lethal complication of chemotherapy in children
    • A description of a new method of vascular access (i.e., making it possible to hemodialyse children)
    • The successful treatment of one of the dreaded complications of the treatment of leukemia
    • The successful use of an immunosuppressive regimen using antithymocyte serum which was developed and produced in Dr. Levey’s laboratory
    • Important contributions to the treatment of a common tumor in children and newborns.  The series of patients treated had the best survival figures in the world
    • Important demonstrations in allogenic bone marrow transplantation bridging the gap between laboratory investigation and clinical use
    • Pioneering work on the evolution and maturation of the immune system
    • Demonstration of the clinical use and importance of a whole new class of immunosuppressive agents
    • Landmark research with Sir Peter Medawar (Nobel Laureate for Medicine 1960) at the National Iunstitutes for Medical Research London including the discovery of anti-lymphocyte serum, the first biological immunosuppresive agent

  • Later, the ajacent MRC Collaborative Centre headed by Dr. Chris Hentschel mentioned in another case study bacame and still is a center of excellence for the development of antibody therapeutics.

 

 
 
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